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3 aminopropionitrile  (Tokyo Chemical Industry)

 
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    Tokyo Chemical Industry 3 aminopropionitrile
    3 Aminopropionitrile, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bapn/aminopropionitrile+%CE%B2/pmc13113578-31-16-17
    Average 86 stars, based on 1 article reviews
    3 aminopropionitrile - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    Control:

    Article Title: The transcription factor RBPJ is required for inflammatory macrophage activation in thoracic aortic dissection by mediating mechanotransduction-induced glycolysis.
    Article Snippet: .. To induce TAD, three-weeks-old male mice were given water containing 0.25% BAPN (Tokyo Chemical Industry Co., LTD, Tokyo, Japan) for 4 weeks, with mice drinking water as a control [48]. ..

    Article Title: Galectin-3 is dispensable for thoracic aortic aneurysmal formation and rupture in mice
    Article Snippet: Immunostaining for Gal-3 and other cell-surface markers was performed using the following antibodies: rabbit anti-Gal-3 antibodies (1 μg/mL; Abcam, ab76245), rabbit anti-α-SMC actin antibodies for smooth muscle cells (1 mg/mL; Abcam, ab5694), rabbit anti-CD68 for macrophages (0.1 mg/mL; Cell Signaling, 97778), rabbit anti-CD31 for endothelial cells (1 μg/mL; Abcam, ab281583), and rat anti-ER-TR7 for fibroblasts (2 μg/mL; Novus Biologicals, NB100-64932). .. Male and female Gal-3 WT and KO mice (3-4 weeks old) were randomly assigned to receive either normal drinking water (vehicle control) or water containing BAPN (0.1%, 0.3%, and 0.5% wt/vol; TCI Chemicals, A0796) for a period of 4 weeks., , Fresh drinking water with and without BAPN was replaced twice per week and monitored daily for any morbidity. ..

    Article Title: Galectin-3 is Dispensable for Thoracic Aortic Aneurysmal Formation and Rupture in Mice
    Article Snippet: Immunostaining for Gal-3 and other cell-surface markers were performed 19 using the following antibodies: rabbit anti-Gal-3 antibodies (1μg/ml; Abcam, ab76245); smooth 20 muscle cells- rabbit anti--SMC actin antibodies (1mg/ml; Abcam, ab5694), macrophages – 21 rabbit anti-CD68 (0.1mg/ml; Cell Signaling, 97778), endothelial cells - rabbit anti-CD31 22 Jo ur al Pr eroo f 6 (1μg/ml; Abcam, ab281583) and fibroblasts – Rat anti-ER-TR7 (2μg/ml; Novus Biologicals, 1 NB100-64932). .. Male and female Gal-3 WT and KO mice (3-4 weeks old) were randomly assigned to 4 receive either normal drinking water (Vehicle control) or water containing BAPN (0.1 %, 0.3 %, 5 and 0.5 % wt/vol; TCI chemicals, A0796) for a period of 4 weeks.3, 10, 11 Fresh drinking water 6 with and without BAPN was replaced twice per week and monitored daily for any morbidity. ..

    Article Title: Transglutaminase 2 activation is involved in thoracic aortic dissection through disruption of endothelial adherens junctions.
    Article Snippet: Thoracic aortic dissection (TAD) is a life-threatening condition.. While medial degeneration is a hallmark of TAD, emerging evidence underscores endothelial dysfunction as a critical initiating event.. However, the specific molecular mediators orchestrating endothelial damage in TAD remain poorly defined.

    Article Title: The transcription factor RBPJ is required for inflammatory macrophage activation in thoracic aortic dissection by mediating mechanotransduction-induced glycolysis
    Article Snippet: .. To induce TAD, three-weeks-old male mice were given water containing 0.25% BAPN (Tokyo Chemical Industry Co., LTD, Tokyo, Japan) for 4 weeks, with mice drinking water as a control [ ]. ..

    other:

    Article Title: Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies.
    Article Snippet: Rh LOXL2 and rhLOXL3 enzymes (R&D Systems, rhLOXL2: 2639- AO-010, rhLOXL3: 6069-AO-010) were treated with PXS-5505 or 5-AZA at indicated concentrations.

    Sterility:

    Article Title: Xuefu Zhuyu decoction attenuates thoracic aortic dissection by regulating VSMC phenotypic switching and oxidative stress via the JAK2/STAT3/HIF-1α pathway.
    Article Snippet: Ethnopharmacological relevance: Xuefu Zhuyu Decoction (XFZY), a classic formula for “blood stasis syndrome”, has insufficient evidence for its thoracic aortic dissection (TAD) therapeutic efficacy and its underlying mechanism remains unclear.. Aim of study: This study aimed to elucidate the efficacy, mechanism, and key components of XFZY against TAD.. Material and method: Using a β-Aminopropionitrile (BAPN)-induced TAD mouse model, efficacy was assessed via survival, ultrasonography, and histology.



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    Reducing matrix stiffness inhibits cervical cancer tumor growth in vivo. ( A ). Mouse footpad lymph node metastasis model: control group (n = 5) received PBS, experimental group (n = 5) received BAPN (50 mg/kg), and tumor size and weight were compared between the two groups; ( B ). Expression levels and quantitative analysis of Collagen I , α-SMA , Fibronectin and MMP9 in mouse tumor tissues detected by immunohistochemistry (scale bar: 50 μm). n = 5 mice per group as biological replicates; 5 random fields per sample for technical quantification. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

    Journal: International Journal of Molecular Sciences

    Article Title: Mechanistic Study of Matrix Stiffness Promoting Lymph Node Metastasis in Cervical Cancer by Regulating NETs Formation via Piezo1

    doi: 10.3390/ijms27125431

    Figure Lengend Snippet: Reducing matrix stiffness inhibits cervical cancer tumor growth in vivo. ( A ). Mouse footpad lymph node metastasis model: control group (n = 5) received PBS, experimental group (n = 5) received BAPN (50 mg/kg), and tumor size and weight were compared between the two groups; ( B ). Expression levels and quantitative analysis of Collagen I , α-SMA , Fibronectin and MMP9 in mouse tumor tissues detected by immunohistochemistry (scale bar: 50 μm). n = 5 mice per group as biological replicates; 5 random fields per sample for technical quantification. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

    Article Snippet: Mice in the BAPN group were intraperitoneally injected with 50 mg/kg BAPN (MedChemExpress, Monmouth Junction, NJ, USA) every 2 days, while the control group received an equal volume of PBS.

    Techniques: In Vivo, Control, Expressing, Immunohistochemistry